Endocrine Abstracts

Introduction: Topoisomerase II alpha is regarded as the important marker of cellular proliferation. Pituitary tumours are usually benign, but some of them are characterized by rapid growth, high recurrence rate and local invasiveness. Proliferation marker Ki-67 most commonly used in pituitary tumours is not entirely reliable as the indicator of the aggressive growth of the lesion. Topoisomerase II alpha expression assessment may be a valuable tool for identification such pitui...

Introduction: Only several cases of co-existing meningiomas and pituitary tumours secreting growth hormone (GH) have been described so far in patients not treated previously with irradiation.Aim: The aim of the study was to describe two cases of co-occurrence of acromegaly and meningioma and to discuss their relationship.Case reports: Case 1. 52-year old female complained of visual disturbances. She was diagnosed with pituitary mic...